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胰岛素样生长因子和子宫内膜异位症的相关关系 被引量:3

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摘要 子宫内膜异位症 (endometriosis,EMs)是一种以子宫腔以外的地方异位子宫内膜组织的出现和生长为特征 ,是妇女生育年龄中妇科的常见疾病。其所致痛经和不孕对女性身心的损害越来越引起人们的重视。最近 ,在体内和体外研究表明 ,内分泌 /旁分泌 /自分泌上所包含的胰岛素样生长因子 (in sulin likegrowthfactors,IGFs)参与子宫内膜异位症患者异位内膜生长的病理生理机制。在严重的子宫内膜异位症情况下 ,异位子宫内膜IGF 1水平较高 ,正位子宫内膜局部IGF 1较低 ,从而可以解释不孕的原因。同时IGF结合蛋白 (IGFBP)
机构地区 西京医院妇产科
出处 《国外医学(妇幼保健分册)》 2003年第2期86-89,共4页 Foreign Medical Sciences (Section of Maternal and Child Health)
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同被引文献21

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