A型肉毒素治疗银屑病一例并文献复习

Botulinum toxin type-A in the treatment of psoriasis: a case report and literatures review

有文献报道A型肉毒素治疗顽固性斑块型银屑病和反转型银屑病效果较好。本文报道A型肉毒素治疗斑块型银屑病患者一例并对相关文献进行复习。患者右小腿外侧皮损作为靶皮损(PASI=7分),注射A型肉毒素,臀部皮损(PASI=6分)为对照靶皮损,无特殊治疗。A型肉毒素注射1个月后回访,右小腿皮疹明显好转,PASI=1分;臀部对照皮损,无明显好转,PASI=5分。

It was reported that Botulinum toxin type-A was effective for treating recalcitrant plaque psoriasis and inverse psoriasis.One patient with plaque psoriasis treated with Botulinum toxin type-A was reported in this paper and related literatures were reviewed.The lesions on the right calf was treated by Botulinum toxin type-A and that on the buttock was as control,with no treatment.The lesion treated by Botulinum toxin type-A improved markedly and the PASI score reduced from 7 to 1 after one month,while the control lesion did not have obvious improvement the PASI score reduced from 6 to 5.