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自体变性骨骼肌修复面神经缺损的实验研究 被引量:3

Experimental study of promoting the facial nerve regeneration through autologous degenerated skeletal muscle
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摘要 目的 探讨修复面神经缺损的新方法。方法  2 2只成年大耳白兔随机分为自体变性骨骼肌组 ,采用自体变性骨骼肌修复兔面神经上颊支 8mm缺损 ,自体神经移植修复组和对照组。并进行电生理、形态学观察和图像分析。结果 术后 2 0周自体变性骨骼肌组面神经缺损获修复 ,其再生神经的形态和电传导功能与自体神经移植组比较差异无显著性 (P >0 0 5 ) ,与正常对照组差异有显著性 (P <0 0 5 )。 Objective To investigate this new method for the facial nerve regeneration after the nerve defects.Methods The 8 mm transectional gap of the bucal branches of the facial nerve was repaired through autologous degenerated skeletal muscle.Reuslts After 20 weeks following the implantation of the autologous degenerated skeletal muscle,all the nerve defects of the experimented animals were repaired finely.In the electrophysiologic indices and morphometeric analysis,the differences between the degenerated skeletal muscle autografts group and the nerve autografts group had no statistical significance(P>0 05),and it had statistical significance between autografts groups and normal control group(0 01<P<0 05).Conclusion The results suggest that the degenerated skeletal muscle could guide facial nerve regenerating effectively.
出处 《解剖学研究》 CAS 2003年第1期45-46,T005,共3页 Anatomy Research
关键词 自体变性骨骼肌 修复 面神经缺损 实验 自体神经移植 电生理 形态学 Facial nerve Regeneration Degenerated skeletal muscle Transplantation
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  • 1钱月楼 吴立连 龙洪清 等.血管植入变性骨骼肌桥接喉返神经缺损的实验研究[J].中华耳鼻喉科杂志,1995,1:75-78.
  • 2Ide C. Nerve regeneration through the basal lamina scaffold at the skeletal muscle. Neurosci Res, 1984,1 : 379 ~ 381.
  • 3Specter JG, Lee P, Peterein J, et al. Facial nerve regeneration through autologous nerve gafts. Laryngoscope, 1991,101 : 527 ~531.
  • 4Glasby MA,Mountain RE,Murray JAM.Repair of the facial nerve using freeze-thawed muscle autogrags. Arch Otolaryngol Head Neck Surg ,1993 ,119 : 461 ~465.

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