济南历下区正常与肥胖儿童发中微量元素含量研究

The Contents of 7 Trace Elements in Hairs of Obese and Normal-weight Children

目的 探索单纯性肥胖儿童体内部分微量元素的水平是否有异于正常体重儿童 ,以及微量元素对儿童生长发育的影响 ,以便更好地为防制儿童肥胖及生长发育缺陷提供科学依据。方法 选取 6 0名年龄在 11～ 14岁之间 ,肥胖度在中度以上的儿童作为肥胖组 ,男女各半 ;再按照成组匹配的原则 ,选取 6 0名正常体重儿童作为对照组。测量两组儿童的形态机能指标及其发中 7种微量元素的含量。结果 肥胖女童发中铝、铜、钡、锰的含量高于对照女童 ;铬、锰、钒的含量有随年龄增长而逐渐降低的趋势。微量元素与多种形态指标间存在显著相关。

Objective To explore the differences between obese and normal-weight children in the contents of seven trace elements, and whether these trace elements influenced growth and development of children.Methods Sixty obese children (30 boys and 30 girls, aged from 11 to 14 years, their weight ≥130% of weight-for-height) were assigned to obese group. Sixty normal-weight children (their weight ranged 90～110% of weight-for-height), matched on the basis of age, sex, class, and socioeconomic state, were chosen as control group. Data on morphological and functional parameters and the contents of these trace elements in hairs were obtained from all subjects. Results Obese girls had higher contents of Al, Cu, V, and Mn in hairs. There was a trend toward decreased hair Cr, Mn, V contents with increasing age. The contents of trace elements were significantly correlated to many morphological parameters. Conclusions Among obese children, there is an overall increasing tendency in the contents of trace elements, and the contents are correlated to many morphological parameters. Al, V, Cr, and I might be risk factors for body fat accumulation. The increased contents of Mn and Cr might be good predictors to central obesity.