氧气驱动肾上腺素雾化吸入治疗毛细支气管炎疗效观察

A study on the clinical effects of nebulized epinephrine on bronchiolitis in infants

目的:探讨快速缓解毛细支气管炎(毛支)患儿喘憋、咳嗽及呼吸困难的治疗方法。方法:将50例毛支患儿随机分为肾上腺素组和普米克令舒组,两组均在综合治疗基础上,肾上腺素组25例加用肾上腺素雾化吸入,普米克令舒组25例加用普米克令舒雾化吸入,对治疗前后症状和体征改善情况、气道阻力参数进行比较。结果:肾上腺素组在缓解喘憋、症状缓解所需时间、改善肺功能、降低气道阻力均明显优于普米克令舒组(P<0.05)。结论:在综合治疗基础上加用氧气驱动肾上腺素雾化吸入是快速缓解毛支患儿喘憋、呼吸困难的有效、安全方法之一,并可缩短住院天数。

Objective : To study the therapeutic methods of rapid improvement in respiratory symptoms (such as wheezing,cough and dyspnea) in infants with bronchiolitis , Methods: 50 cases were divided into two groups randomly . 25 cases in control group were treated with pulmicort respules nebulization and 25 cases in the other group were treated with epinephrine nebulization (using a nebulizer driven at 6-8L/min by continuous oxygen flow) besides the same comprehensive therapy for both groups, the same synthetic therapy . The clinical effects and pulmonary function were evaluated in both groups. Results: The group with nebulized epinephrine showed a rapid improvement in respiratory symptoms (such as wheezing,cough and dyspnea) and airway obstruction. The days of hospitalization were obviously fewer in the epinephrine group compared with those in control group . Conclusion: The clinical symptoms of bronchiolitis can be controlled rapidly and the pulmonary function can be improved by using epinephrine nebulization driven at 6-8L/min by continuous oxygen flow, which is safe, by using effective and without any side -effects.