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血脑屏障紧密连接的分子基础及信号调节 被引量:4

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摘要 脑微血管内皮细胞之间的紧密连接 (TJ)是血脑屏障的结构基础及特点。跨膜蛋白、胞质附着蛋白及细胞骨架蛋白共同组成了TJ ,钙离子、胶质细胞分泌物、蛋白质的磷酸化等内源性、外源性的信号通路通过调节这些蛋白以达到对血脑屏障通透性的调节 ,这是生理。
出处 《国外医学(生理病理科学与临床分册)》 2003年第2期165-167,共3页 Foreign Medical Sciences(Pathophysiology and Clinical Medicine)
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