轮状病毒肠炎和鼠伤寒杆菌肠炎患儿粪便中SIgA含量测定

Fecal secretory immunoglobulin A in the children with rotavirus enteritis or salmonella typhimurium enteritis

用放射免疫法(双抗体—PEG法)测定正常婴幼儿和轮状病毒肠炎及鼠伤菌肠炎各40例患儿粪便中SIgA的含量。结果表明轮状病毒肠炎及鼠伤寒杆菌肠炎之间粪便中SIgA含量无明显差异,而二者粪便中SIgA含量明显高于正常对照组。提示肠道SIgA在婴幼儿轮状病毒肠炎及鼠伤寒杆菌肠炎恢复中起重要作用。

From December 1990 to April 1991, fecal secretory immunoglobulin A (SIgA) was detected with radio-immunoassay (dual antibodies-PEG) in 40 normal children, 40 children with rotavirus enteritis and 40 children with salmonella typhimurium enteritis. There was no significant difference in the fecal SIgA contents between the rotavirus enteritis group and the salmonella typhimurium enteritis group, but their fecal SIgA contents were markedly higher than that of the normal group. This may indicate that enteritic SIgA plays an important role in children with rotavirus enteritis and salmonella typhimurium enteritis.