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肾素血管紧张素系统与糖尿病肾病 被引量：6

Renin-angiotensin system and diabetic nephropathy
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摘要 肾素血管紧张素系统是生理功能颇为复杂的内分泌系统 ,广泛存在于机体各个组织。该系统的关键基因决定着个体的糖尿病肾病易感性。血管紧张素Ⅱ通过细胞外基质成分合成增多、降解减少而促使肾小球硬化。 Renin angiotensin system is an endocrine system with complex physiological functions, existing in many tissues. Its key genes predispose the subject's diabetic nephropathy. Angiotensin can promote the glomerulosclerosis by increasing the production and decreasing the degradation of extrocellular matrix. Angiotensin converting enzyme inhibitors and angiotensin receptor antagonists have the protection function of diabetic nephropathy independent of blood pressure.
作者 刘红 杨卉
机构地区 山东省烟台市烟台山医院药剂科
出处 《安徽医药》 CAS 2003年第2期84-86,共3页 Anhui Medical and Pharmaceutical Journal
关键词 肾素血管紧张素系统 糖尿病肾病 血管紧张素转换酶抑制剂 血管紧张素受体拮抗剂 renin angiotensin system diabetic nephropathy angiotensin converting enzyme inhibitors angiotensin receptor antagonists
分类号 R587.2 [医药卫生—内分泌]
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参考文献19

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  • 4吴松华,项坤三,郑泰山,孙多奇,翁青,李杰.肾素-血管紧张素系统三个关键基因与2型糖尿病肾病发病关系的研究[J].中华内分泌代谢杂志,2001,17(6):331-334. 被引量：12
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二级参考文献21

  • 1吴松华,项坤三,翁青,林辛,李青,戴又坚,沈卫平,浦鎏,李杰.糖尿病肾病与血管紧张素I转换酶基因多态性的关系[J].中华医学杂志,1997,77(3):183-186. 被引量：22
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安徽医药
2003年 第2期

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