2Han H,Cliff CL,Harley LH.Accelerated assembled of Gquadruplex structures by a small molecule[J].Biochemistry,1999,38(22):6 981~6 986.
3Mitchell JR,Collins K.Human telomerase activation requires two independent interactions between telomerase RNA and telomrase reverse transcriptase[J].Mol cell,2000,6(2): 361—371.
4Liu Y,Snow BE, Hande MP, et al. Telomerase-associated protein TEP1 is not essential for telomerase activity or telomere length maintenance in vivo[J]. Mol Cell Biol, 2000,20(21):8178--8 184.
5Kim NW, Piatyszek MA, Prowse KR, et al. Specific Association of human telomerase activity with immortal cells and cancer[J]. Science,1994,266(5193):2 011--2 015.
6Mackenzie KL, Franco S, May C. Mass cultured human fibroblasts overexpressing hTERT encounter a growth crisis following an extended period of proliferation[J]. Exp Cell Res,2000,259(2): 336 -- 250.
7Hisatoni H,Nagao K, Kanamaru T et al. Levels of telomerase subunit mRNA as a predictor of potential malignancy[J]. Int J Oncol, 1999,14(4) :727-732.
8Zhang X, Mar V, Zhou W, et al. Telomere shortening and apoptosis in telomerase-inhibited human tumor cells[J]. Genes Dev,1999,13(18):2 388--2 399.
9Funk WD, Wang CK, Shelton DN, et al. Telomerase expression restores dermal intergrity to vitro-aged fibroblasts in a reconstituted skin model[J]. Exp cell Res,2000,258(2):270--278.
10Steinert S, Shay JW,Wright WE. Transient expression of human telomerase extends the life span of normal human fibroblasts[J]. Biochem Biophys Res Lommun, 2000, 273(3):1 095--1 098.
5Yu J, Guo Q L, You Q D, et al. Repression of telomerase reverse transcriptase mRNA and hTERT promoter by gambogic acid in human gastric carcinoma cells [J]. Cancer Chemother Pharmacol, 2006,2(10) : 1-10.