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荧光定量PCR检测巨细胞病毒在婴幼儿肺炎中的应用

Fluorescence quantitative PCR detection cytomegalovirus pneumonia in infants and young children the application
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摘要 目的:探讨人巨细胞病毒(HCMV)在婴幼儿肺炎中的感染情况。方法:采集符合临床诊断标准的婴幼儿肺炎患儿尿液,应用荧光定量PCR技术检测HCMV-DNA。结果:234例肺炎患儿中,114例检测结果阳性,120例检测结果阴性,阳性率为48.72%。结论:在婴幼儿肺炎中,HCMV的感染率较高,应引起临床重视,做到早期诊断以利治疗。 Objective To study the human cytomegalo virus(HCMV) infection in infants of pneumonia infection status.Methods Collecting conform to the clinical diagnosis standard infant pneumonia children urine,the application of fluorescence quantitative PCR technical detection HCMV-DNA.Results All 234 cases of pneumonia in children,114 cases of detection result is positive,120 cases of test results negative,positive rate was 48.72%.Conclusion In infant pneumonia,of HCMV infection rate is higher,should cause clinical attention,do early diagnosis and treatment.
机构地区 河北省儿童医院
出处 《中国美容医学》 CAS 2012年第12X期508-509,共2页 Chinese Journal of Aesthetic Medicine
关键词 巨细胞病毒感染 HCMV 婴幼儿肺炎 cytomegalovirus infection,HCMV,Infant pneumonia
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  • 1中华儿科学会感染消化学组.全国小儿巨细胞病毒感染学术会议纪要(附巨细胞病毒感染诊断试行标准)[J].中华儿科杂志,1995,33(1):7-9.
  • 2刘兰青 吕绳敏 等.巨细胞病毒感染引起的小头畸形及其他神经损害[J].中华实验和临床病毒学杂志,1989,13:40-42.
  • 3Wills MR,Okecha G,Weekes MP,et al.Identification of naive or antigen-experienced human CD8(+) T cells by expression of costimulation and chemokine receptors:analysis of the human cytomegalovirus-specific CD8(+) T cell response.J Immunol,2002,168(11):5455-5464.
  • 4Kuijpers TW,Vossen MT,Gent MR,et al.Frequencies of circulating cytolytic,CD45RA+ CD27-,CD8+ T lymphocytes depend on infection with CMV.J Immunol,2003,170(8):4342-4348.
  • 5Elbou-Ould MA,Luton D,Yadini M,et al.Cellular immune response of fetuses to cytomegalovirus.Pediatr Res,2004,55 (2):280-286.
  • 6Aubert G,Hassan-Walker AF,Madrigal JA,et al.Cytomegalovirus-specific cellular immune responses and viremia in recipients of allogeneic stem cell transplants.J Infect Dis,2001,184(8):955-963.
  • 7Cwynarski K,Ainsworth J,Cobbold M,et al.Direct visualization of cytomegalovirus-specific T-cell reconstitution after allogeneic stem cell transplantation.Blood,2001,97(5):1232-1240.
  • 8Reusser P,Attenhofer R,Hebart H,et al.Cytomegalovirus-specific T-cell immunity in recipients of autologous peripheral blood stem cell or bone marrow transplants.Blood,1997,89(10):3873-3879.
  • 9Gratama JW,Cornelissen JJ.Diagnostic potential of tetramerbased monitoring of cytomegalovirus-specific CD8+ T lymphocytes in allogeneic stem cell transplantation.Clin Immunol,2003,106(1):29-35.
  • 10Foster AE,Gottlieb DJ,Sartor M,et al.Cytomegalovirus-specific CD4+ and CD8+ T-cells follow a similar reconstitution pattern after allogeneic stem cell transplantation.Biol Blood Marrow Transplant,2002,8(9):501-511.

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