跟骨定量超声评价骨质量

EVALUATION OF THE QUALITY AND QUANTITYOF BONE WITH QUS

目的 :探讨跟骨定量超声 ( QUS)的临床价值。方法 :对骨科门诊自愿受试者行 QUS测值并随机取1 97例拟诊为原发性骨质疏松 ( OP)的中老年病人作统计学分析 ;其中 1 49例以宽波段超声衰减 ( BUA)、T-score( T评分 )、Z-score( Z评分 )及年龄为变数 ;48例经 SPSS软件处理分析 Singh分级骨强度指数 ( Singhindex)与 QUS中的 BUA、声速 ( SOS)、硬度指数 ( STI)的相关性。结果 :( 1 ) 1 49例 BUA、T-score均随增龄递减( P <0 .0 0 1 ) ;( 2 ) BUA在 8个对应组中差异显著或非常显著 ( P <0 .0 1或 P <0 .0 0 1 ) ;( 3 )用药治疗前后的BUA、T-score与 Z-score均有显著差异 ( P <0 .0 0 1 ) ;( 4 ) BUA(及 STI)与 Singh index显著正相关 ( P <0 .0 0 1 )。结论 :QUS评价骨质量具有量化、简易、省时、廉价、无辐射损伤等优点 ,相对科学 ,可用于 OP的诊断与药物治疗 。

Objective: To explore the clinical value of quantitative calcaneus ultrasound (QUS). Methods: The volunteers of orthopaedic outpatient service were checked by QUS and 197 middle\|elder patients with osteoporosis (OP) were selected randomly to be statistically analysed. In 149 of them, BUA (broadband ultrasound attenuation), T\|score, Z\|score and age were as the parameters. 48 of them were dealt with the soft ware of SPSS to analyse the correlation between their Singh index and BUA, SOS (speed of ultrasound), STI (stiffness index). Results: (1) BUA, T\|score, in 149 cases were reducing as aging (P<0 001). (2) Significant or very significant difference in BUA exists between every\|relevant double among 8 groups (P<0 01 or P<0 001). (3) A very significant difference in BUA, T\|score, Z\|score exists before and after the drug treatment for OP (P<0 001). (4) BUA (and STI) has a significant correlation with Singh index (P<0 001). Conclusion: Evaluating the quality and quantity of bone by QUS has advantage, having quantitative evaluation, sparing time and money, and no radioactive damage, being a relatively scientific method, can direct the choice of treatment of fractures, can use to diagnose OP and the drug treatment.\;