米非司酮治疗子宫肌瘤的临床观察

The clinical study of mifepristone treatment for uterine leiomyomas

目的:探讨米非司酮治疗子宫肌瘤的疗效。方法:对愿意接受米非司酮治疗的子宫肌瘤患者,每天口服米非司酮12.5mg,三个月为一疗程,接受复查。结果:口服米非司酮可引起闭经、改善贫血;停药后月经复潮,可使经量减少、经期缩短;子宫体积、最大肌瘤体积缩小;部分更年期妇女用药后进入绝经期。结论:米非司酮是治疗子宫肌瘤的有效药物。

Objective To study the effects of mifepristone in treating uterine leiomyoma. Methods Forty women with uterine leiomyoma were in our study. They were all treated with mifepristone 12.5mg/day for three months. Results The clinical symptoms improved obviously in these patients. Mifepristone lead to menoschesis and ameliorating anaemia. It also could shorten menses and reduce menstrual bleeding when the patients menstruate coming back .Some premenopause women became menopause. Conclusions Mifepristone is an effective medicine in uterine leiomyoma treatment.