嗜铬细胞瘤的手术治疗:11例报告

Operative Treatment of Pheochromocytoma:Report of 11 Cases

背景与目的:嗜铬细胞瘤临床上少见,无高血压或无其他症状者容易误诊,手术切除可治愈,但在术前无准备或准备不充分情况下手术风险极大。本文报告我们手术治疗嗜铬细胞瘤的经验。方法:回顾性分析11例嗜铬细胞瘤患者的临床资料,着重总结该病手术前、手术中控制血压的方法和手术经验。结果:11例患者均手术成功切除肿瘤,术后随访3个月～10年,全部病例血压恢复正常,症状消失。1例术后半年在腰交感链部位肿瘤复发,再次手术切除后治愈。结论:嗜铬细胞瘤最根本的治疗是手术切除,充分的术前准备和手术技巧是保证手术成功的关键。

BACKGROUND &OBJECTIVE: Pheochromocytoma is clinically uncommon. Pheochromocytoma patients without hypertension or symptoms are often misdiagnosed. The patients could be cured by surgical removal of the tumor. However, surgery is dangerous if the preoperative preparation was not well done. The authors reported their experiences in surgical treatment of pheochromocytoma.METHODS:Clinical data of 11 patients with pheochromocytoma were reviewed retrospectively to summarize the management of blood pressure during pre operation and operation. RESULTS: After excision of the tumors, 11 patients have been followed up for 3 months to 10 years. Blood pressure became normal and symptoms vanished in all patients. Only one patient recurred at paraveterbral sympathetic chain 6 months after operation and underwent another operation for removal of the tumor. CONCLUSION: Surgery is the mainstay of therapy for pheochromocytoma. The adequate preoperative preparation is very important for successful surgery.