药疹484例临床分析

Clinical Analysis of 484 Cases of Drug Eruptions

了解常见药疹的临床表现及常见的致敏药物。对 484例药疹进行回顾性分析。临床表现以荨麻疹型最常见 (1 87例 ) ,致敏药物以抗生素最多 (2 0 6例 ) ,值得注意的是中成药致敏占 3 6例。其中 8 1 %的患者本次致病药物与既往致病药物完全相同 ,46 5 %的患者由 2种或 2种以上药物引起。提示临床医师用药时 ,切忌对已有药敏史者再用原致敏药物或化学构造上相似的药物 ,严格掌握用药指征 。

In order to learn the clinical symptom of drug eruptions and familiar allergenic drugs, 484 cases of drug eruptions in retrospective were analyzed. The most familiar symptom is urticaria, numbering to 187; the most allergenic drugs are antibiotics numbering to 206; the most remarkable thing is that Chinese Traditional Medicine also induce anaphylaxis, and the cases amount to 36. About 8 1% patients are induced anaphylaxis are with former drugs inducing anaphylaxis; about 46 5% patients are induced anaphylaxis by two or more sorts of drugs. It is important to clinic doctors that not prescribe drugs had induced anaphylaxis or have analogical structure with allergenic drugs to patients, master the therapeutic symptom and apply antibiotics reasonably.