自体血液回输对脊柱手术病人血常规的影响

Effect of Intro-operative Autotransfusion of Blood onBlood Routine in Spinal Anterior Surgery

目的 :探讨脊柱前路手术中自体血液回输对血常规的影响 ,评估其临床应用的安全性。方法 :脊柱前路手术患者 4 5例分为两组 ,Ⅰ组 :自体血液回输组 (n =2 7) ,Ⅱ组 :非自体血液回输组 (n =18)。对两组病人术前、术后第1天、第 7天的血常规进行观测。结果 :两组术后血常规变化规律一致 ;分别比较术前、术后第 1天、第 7天两组间血常规 ,均无显著性差异。组内白细胞 (WBC)计数、中性粒细胞含量 (neut% )在术后有一过性显著增高 (自体血液回输组为P <0 .0 1,异体血输入组为P <0 .0 5 ) ,术后第 7天两组均恢复正常 (P >0 .0 5 )。红细胞 (RBC)计数、血红蛋白含量 (Hgb)、红细胞比积 (Hct)均较术前有显著降低 (P <0 .0 5 )。未发现应用自体血液回输出现并发症。结论 :自体血液回输仅对血小板有破坏、清除 ,对其他血液成分无明显影响。

Objective: To study the effect of intro operative autotransfusion on blood routine and to evluate the safety of its clinical application.Methods:Forty five patients who underwent anterior operation on for thoracolumbar fractures, were divided into two groups:group I:autotransfusion group( n =27),group II:non autotransfusion group( n =18).Routine blood tests were examined for the blood samples taken in preoperation,On 1st and 7th days postoperation.Results:The preoperative and postoperative various parameters of rountine blood in autotransfusion group were similar to those in non autotransfusion group.In the two group,WBC and neut% were higher on 1st day of postoperation than that preoperative(in autotransfusion group P <0.01,in non autotransfusion group P <0.05),but reduced to normal on 7th day of postoperation.RBC,Hgb and Hct were statistic lower in postoperation than preoperation. In the study, complication of intraoperative autotransfusion was not observed. Conclusion: There is no significant effect of intraoperative autotransfusion on blood routine except for blood platelet. Clinical application of intraoperative autotransfusion in spinal operation would be safe.