中药材指纹体系

Fingerprint system of Chinese medicinal materials

建立反映中药材整体信息的指纹体系是现阶段全面、有效控制中药材质量的手段。中药材指纹体系是采用化学指纹图谱和基因指纹图谱来分别表述、控制中药材的多元化学组份和源于生物体的特性 ,从有效成分和遗传物质两方面实现对中药材质量的控制。基因指纹图谱可从遗传物质上进一步佐证中药区别于化学药品的特性。基因指纹与化学指纹相结合 ,对于中药的品种鉴定、质量评价、药用优良品种的选育都具有重要的意义。实施中药材指纹体系 ,首先要建立药典品种的含多种检测方法的化学指纹和基因指纹图谱库 ,其次要建立指纹图谱的计算机模式识别系统。

A novel fingerprint system of Chinese medicinal materials employing both DNA and chemical means has been proposed. To establish the fingerprint system is very effective to the quality control of Chinese medicinal materials, because it will be controlled from chemical substance and genetic information. The chemical components and DNA fingerprints will show the complex chemical components and biological source, respectively. DNA fingerprint could give a further proof to distinguish Chinese materia medica from the chemical. The combination of chemical and DNA fingerprints is constructive to quality control of Chinese materia medica, the cultivar identification and the selective breed of good varieties for medicinal use. To carry out the fingerprint system of Chinese medicinal materials, it is necessary to establish fingerprint database of Chinese medicinal materials, including chemical and DNA fingerprint, as well as many detection methods, and the pattern recognition system by computer is also necessary.