苦马豆果皮的甾醇类成分研究

Stigmasterols from pericarp of Sphaerophysa salsula

目的 研究豆科苦马豆属植物苦马豆Sphaerophysasalsula果皮中的化学成分。 方法 利用硅胶柱色谱分离纯化 ,根据理化性质和光谱数据进行结构鉴定。结果 从苦马豆果皮中得到 4个化合物 ,分别鉴定为 :5α 豆甾 3 酮 (5α stigmast 3 one ,Ⅰ ) ,5α 豆甾 3,6 二酮 (5α stigmasta 3,6 dione ,Ⅱ ) ,豆甾 4 烯 3 酮 (stigmast 4 en 3 one ,Ⅲ ) ,3β ,6 β 豆甾 4 烯 3,6 二醇 (3β ,6 β stigmast 4 en 3,6 diol,Ⅳ )。结论 化合物Ⅰ～Ⅳ为该属植物中首次分得。

Object Isolation and structural determination of the chemical constituents from the 95% ethanol extract of the pericarp of Sphaerophysa salsula (Pall.) DC. Methods To isolate chemical constituents, solvent extraction together with column chromatography was used. Physico-chemical characters and spectroscopic analysis were employed for structural identification. Results Four compounds were identified as 5α-stigmast-3-one (Ⅰ), 5α-stigmast-3, 6-dione (Ⅱ), stigmast-4-en-3-one (Ⅲ), 3β, 6β-stigmast-4-en-3, 6-diol (Ⅳ). Conclusion All these compounds were first isolated from the plants of Sphaerophysa DC.