摘要
目的 观察补虚祛瘀法治疗类风湿性关节炎 (RA)的临床疗效。方法 3789例类风湿性关节炎患者随机分为 2组 ,治疗组 31 6 6例 ,采用补虚祛瘀法治疗 ,口服自拟补脾消痹丸 (汤 ) ,对照组 6 2 3例 ,口服消炎痛和雷公藤片。 2组均 3个月为 1个疗程。结果 治疗组临床总有效率为 98.7% ,总显效率为 4 8.0 % ,毒副反应发生率为 9.6 6 % ;对照组临床总有效率为 76 .1 % ,总显效率为 1 2 .0 % ,毒副反应发生率为 2 1 .1 8% ,2组比较总有效率、总显效率、毒副反应发生率均有显著性差异 (P <0 .0 1 )。治疗组在减轻关节疼痛及肿胀 ,改善关节功能 ,降低红细胞沉降率 (ESR)、类风湿因子 (RF)水平 ,X线分期改善及远期缓解率方面均优于对照组 (P <0 .0 5 ,P <0 .0 1 )。
Objective To observe the effect of method of removing blood stasis and invigorating for deficiency in treating rheumatoid arthritis. Methods 3789 patients with rheumatoid arthritis were randomly divided into treatment group (n=3166), which were treated by oral administration of Bupixiaobi, and control group (n=623), which were treated by indomethacin and tripterygium wilfordii. The course was 3 months in both groups. Results The total effective rate in treatment group (98.7%) was higher than that in control group (76.1%, P<0.01). The side effect rate in treatment group (9.61%) was lower than that in control group (21.18%, P<0.01). The improvements of joint function, display of image and reducing articular pain in treatment group were superior to those in control (P<0.05). Conclusion A method of removing blood stasis and invigorating for deficiency could produce a definite effect on rheumatoid arthritis.
出处
《河北中医》
2003年第5期332-334,共3页
Hebei Journal of Traditional Chinese Medicine