三种电解质分析仪结果可比性研究

The comparative study on three kinds of electrolytic analyzer

目的 为提高同一实验室不同电解质仪器测定结果的可比性。方法 对A、B、C不同厂家 3台仪器 (CIBACORNING 6 4 4 ,BECKMENEL3,NOVA5 + )的准确度、重复性、线性范围进行评价 ,选定其中 1台 3项指标最优的仪器 (A)作为比对仪器。每天随机选取高、中、低值病人的新鲜血清 8份 ,同时在 3台仪器A、B、C上检测 ,共分析 5d ,利用比对仪器的检测结果对其他仪器进行校正。结果 B仪器检测结果与A仪器比较 ,K+ 、Na+ 相关性好 (r =0 9977,r =0 976 4 ) ,Cl-相关性较差 (r =0 9133) ,但除K+ 浓度为 6mmol/L时的相对偏差较大外 (2 8% )其余医学决定水平值的相对偏差均小于 1 6 %。C仪器与A仪器比较 ,K+ 、NA+ 相关性好 (r=0 9975、r =0 9891) ,Cl-相关性稍差 (r =0 95 5 4 ) ,各项目医学决定水平值的相对偏差为 2 3%～ 7 5 %。用比对仪器的测定结果进行校正后 ,B、C仪器的测定结果与A仪器比较 ,相关系数均大于 0 975 ,相对偏差均小于 1 6 %。结论 利用比对仪器测定新鲜血清的结果来校正其他仪器 ,可以使不同的电解质仪器间的检测结果具有可比性。

Objective To improve the comparison of the results determined by three different electrolytic analyzer in the same laboratory. Method To evaluate the accuracy, reproducibility and liner range of the following three analyzers (CIBA CORNING 644, BECKMEN EL3 and NOVA5+). The analyzer with the best three indices (A) worked as a comparative one. 8 fresh serum samples of patients were analyzed by the three analyzers at the same time each day. After 5 operation days, we corrected the other two analyzer′s results by the comparable one. Results There were good relativity of the results of Na+ and K+ between B and A r Na+=0.976 4, r K+=0.997 7 and a little poor relativity og Cl-(r=0.913 3). The deviation of medical decision level was within 1.6 except the K+ concentrate 6 mmol/L. The relativity of result of Na+ and K+ were good between the C and A r Na+=0.989 1, r K+=0.997 5 and relativity of the result of Cl- was a little poor (r=0.955 4). After correcting B and C by A, the result determined by B and C were comparable (r>0.975). The deviation of medical decision level was within 1.6. Conclusion Comparison among various analyzers were improved after the other analyzers corrected by the one comparable analyzer through the result of the fresh serums determined by it.