摘要
L-苯基乙酰基甲醇(L-Phenylacetylcarbinol, L-PAC)在制药业中被用作前体来合成L-麻黄素(L-ephedrine)、D-伪麻黄素(D-pseudoephedrine),在医学上,麻黄素可用来治疗低血压和哮喘,并有利尿之功效[1].近些年有报道指出,L-麻黄素可用于减肥[2].另外,L-PAC还可以用于合成安非他明(amphetamine),苯丙胺和苯胺等药物[3].
As an important drug intermediate, L-Phenylacetylcarbinol ( L-PAC) can be produced by biotransformation of benzaldehyde via microbial strains. Methods of reducing toxicity and some other foctors affecting L-PAC bioconversation were reviewed. Ref 36
出处
《应用与环境生物学报》
CAS
CSCD
2003年第2期218-220,共3页
Chinese Journal of Applied and Environmental Biology
