骨折修复的启动与分子水平的调节

INITIATION OF FRACTURE REPAIR AND REGULATION ON MOLECULAR LEVEL

目的 阐明骨折修复的启动以及相关因子在分子水平上对启动的调节。 方法 广泛查阅近年来有关骨折修复及其相关因子在此过程中的不同作用和研究进展的相关文献 ,总结骨折修复启动过程及其关系紧密的调节因子在其中的作用 ,探讨干预此过程的方法。 结果 在骨折修复过程中 ,其启动具有明显的特征 ,在启动的同时有着关系密切的相关因子参与其中每一个环节。 结论 在分子水平上 ,骨折修复的启动有着特殊的相关因子如骨形成蛋白、转化生长因子 -β等参与调控。

Objective To investigate the initiation of fracture repair and regulation on molecular level. Methods Literature concerned fracture repair and effects of correlative factors in the process in recent years was reviewed. The initiation in the process of fracture repair and the effects of the correlative factor were summarized to probe into effective methods to intervene. Results During fracture repair, the initiation had particular character and the correlative factors were concerned with the process. Conclusion The correlative factors regulate the initiation of fracture repair on molecular level.