胸腺瘤外科治疗

Report on surgical treatment of thymoma in 96 patients

目的 对96例胸腺瘤进行临床分析,了解胸腺瘤手术与分期、预后的关系。方法 总结96例胸腺瘤患者,按Masaoka分期法进行分期。分析不同分期胸腺瘤与生存率之间关系。结果完整手术切除83例(86.5％),姑息性切除9例(9.4％),探查活检4例(4.2％),死亡1例(1.04％)。5年、10年生存率Ⅰ期为91.4％、84.5％,Ⅱ期为70.6％、52.9％,Ⅲ期为50.0％、28.6％,Ⅳa期为14.3％、0。结论 胸腺瘤治疗应尽可能完整切除肿瘤及部分周围组织,以达到手术彻底切除。Masao-ka分期是主要预后因素。

Objective To analyze the characteristics of operation and the prognosis in 96 patients with thymoma.Methods Data of 96 patients operated for thymoma were collected.The distribution according to Masao-ka staging showed stage I in 58 patients,stage II in 17 cases,stage III in 14 cases,and stage IVa in 7 cases.The relation between stage and survival rate was analyzed. Results Of the 96 patients 83 underwent complete resection,9 underwent palliative operation,and 4 were biopsied only. One patient died of operation.The 5- and 10- year survial rates were 91.4% ,84.5% for stage I ,70.6% ,52.9% for stage II ,50.0% ,28.6% for stage III, 14.3% ,0 for stage IVa,respectively. Conclusion The best treatment for thymoma is to resect it as completely as possible. Masaoka's clinical staging is an important prognostic factor.