异位妊娠患者腹腔及外周血孕酮和β-hCG的测定

Detection of Progesterone and β-hCG in Hemoperitoneum and Serum of Ectopic Pregnancy Patients

目的 探讨异位妊娠患者腹腔游离血及外周血孕酮(P)、人绒毛膜促性腺激素(β-hCG)与异位妊娠(EP)发生、发展的关系。方法 用电化学发光法测定所有EP腹腔游离血及外周血样本的P和β- hCG。结果 腹腔游离血P及β-hCG分别高于外周血P和β-hCG(P<0.001,P<0.001),且腹腔游离血P、β-hCG分别随外周血P、β-hCG升高而上升(P=0.001,P<0.05),同时外周血P随β-hCG降低而降低(P<0.0001)。腹腔游离血P、外周血P越高,腹腔出血量越多(P<0.01,P<0.05)。但不同停经时间、阴道出血时间与腹腔游离血P、β-hCG、外周血P、β-hCG均无明显关系(P>0.05)。破裂型与流产型EP的外周血、腹腔游离血P之间、β-hCG之间均无差异(P>0.05)。结论 腹腔游离血及外周血P、β-hCG在EP的发生、发展及早期诊断中有重要作用。

Objective To discuss the relationship between progesterone and p-hCG in hemoperitoneum and serum and the development of ectopic pregnancy. Methods 35 cases of ectopic pregnancies were detected for progesterone and β-hCG in hemoperitoneum and serum by the method of electrochemiluminescence. Results Progesterone and β-hCG was higher in hemoperitoneum than in serum, and there was a significant difference between them (p < 0.001) . Progesterone and β-hCG in hemoperitoneum raised with the raise of it in serum, and progesterone in serum decreased with the decrease of β-hCG (p < 0.001). The volume of hemoperitoneum was related to the progesterone in hemoperitoneum and serum. But the time of pregnancy and vaginal bleeding were not significantly related to progesterone and β-hCG in hemoperitoneum and serum (p > 0.05). There was no significant relationship between niptured and abortive ectopic pregnancy on progesterone and β-hCG in hemoperitoneum and serum. Conclusions It is significant for progesterone and β-hCG in hemoperitoneum and serum in early diagnosing ectopic pregnancy.