2-(2,4-二氯苯基)-1,2-环氧己烷的合成

Synthesis of 2-(2,4-dichlorophenyl)-1,2-epoxyhexane

杀菌剂己唑醇中间体 2 ( 2 ,4 二氯苯基 ) 1,2 环氧己烷 ( 1)的合成步骤如下 :以 2 ,4 二氯苯基戊酮 ( 1)为原料 ,用硫叶立德 (CH3) 3S+ CH3SO- 4为环氧化试剂 ,在碱性条件下得到 ( 1) ,收率≥95 %,产品含量≥ 95 %,此合成工艺反应条件温和易控。

dichlorophenyl)-1,2-epoxyhexane(1) was synthesized according to the following procedures. Compound (1) was prepared by reaction of 2,4-dichlorophenylpentanone(2) with (CH 3) 3S +CH 3SO - 4 which as sulphonium yield under base condition. The yield is up to 95% and the purity is over 95%. The reaction is mild and easy to be controlled.