摘要
取新西兰健康家兔36只(其中26只造模),分正常对照组10只,化痰治疗组8只,消瘀治疗组8只,治疗空白组10只,观察化痰和消瘀两法对家兔动脉粥样硬化(As)的作用效果。结果表明化痰法对家兔As模型的抑制作用优于消瘀法,化痰法不仅具有降脂、抗自由基的作用,而且能有效地调节PGI_2-TXA_2的平衡。认为家兔As初期病机可能是以痰浊内阻为主。
36 Newzealand rabbits were divided into normal group(10), Expelling phlegm treatment group(8), Dispersing blood stasis treatment group (8) and control group (10) and the effects of Expelling phlegm and Dispersing blood stasis treatments on rabbit artheriosclerosis model were observed. The results indicated that Expelling phlegm treatment could not only alleviate hyperlipidemia and diminish free radicle activity, but also regulate the balance between PGI_2 and TXA_2 effectively and presented stronger inhibition of artherosclerosis in rabbits than Dispersing blood stasis treatment. It is deduced that internal blockage of phlegm and turbid matter is the major pathogenesis of primary artherosclerosis in rabbits.
出处
《湖南中医学院学报》
1992年第1期33-35,共3页
Journal of Hunan College of Traditional Chinese Medicine
关键词
动脉粥样硬化
病理学
祛痰
消瘀
aorta/anatomy& histology
aorta/pathology
coronary vessels/anatomy &/histology
coronary vessels/pathology
atherosclerosis/pathology
expelling phlegm
dispersing blood stasis
comparative study
rabbits
