暴发性急性胰腺炎早期手术治疗效果观察

Effects of early operation on fulminant acute pancreatitis

目的 探讨暴发性急性胰腺炎 (FAP)早期治疗的效果。方法 2 0 0 0年 1月至 2 0 0 2年 3月收治FAP2 5例。试用非手术和早期手术疗法进行治疗并观察疗效。结果 单纯非手术疗法 3例无存活 ;非手术疗法结合血液滤过 3例存活 1例 ;非手术治疗无效作早期手术 9例存活 8例 ;血滤后手术治疗 10例存活 7例。总体生存率为 6 4 % (16 / 2 5 )。结论 FAP早期手术治疗能防止MODS的继续发展 。

Objective To investigate the effects of early operation on fulminant acute pancreatitis(FAP).Methods From Jan,2000 to Mar,2002,25 patients with FAP were hospitalized to department of surgery in Ruijin Hospital.The patients were rescued with nonoperative therapy and early operation,and the effects were observed.Results The effects of each method are:3 with nonoperative method not survival;3 combined with hemofiltration,1 survival;9 with early operation,8 survival;10 with hemofiltration followed by operation,7 survival.The overall survival rate was 64%(16/25).Conclusion It might concluded that early operation for FAP may prevent MODS from deteriorating.Facilitated intensive care therapy,such as hemofiltration,ventilation with PEEP,is very important for creating an opportunity for operation and improving the recovery after operation.