无乳糖饮食辅助治疗婴幼儿轮状病毒性肠炎疗效观察

Efficacy of lactose-free diet in treatment of rotavirus enteritis of infants

目的 评估无乳糖饮食辅助治疗婴幼儿轮状病毒性肠炎的疗效。方法 将 12 2例轮状病毒性肠炎随机分成 2组。对照组 5 2例 ,采用抗病毒、提高肠粘膜屏障功能、调节肠道微生态、纠正水电解质及酸碱平衡紊乱等治疗 ,继续用平时正常饮食。治疗组 70例 ,在上述治疗基础上 ,加用无乳糖饮食辅助治疗。结果 治疗组止泻天数较对照组平均缩短 1.3 3天 ,呕吐消失时间明显缩短 (P <0 .0 5 ) ,静脉补液天数较对照组平均减少 1.84天 (P <0 .0 1)。结论 采用无乳糖饮食辅助治疗婴幼儿轮状病毒性肠炎可明显改善症状、缩短病程 ,有一定临床实用价值。

Objective To evaluate the therapeutic effect of lactose-free diet on rotavirus diarrhea in infants. Methods 122 infants with rotavirus enteritis were divided into 2 groups randomly, control and study groups. The control group containing 52 cases was treated with antiviral drugs, mucous barrier protestant, modulators of gastrointestinal micro-ecosystem, correction of water-electrolyte and acid-base imbalance, and on routine diet. The study group with 70 cases was treated with the same protocol as the control group except on lactose-free diet.Results The significant difference was found between the two groups in the duration of vomiting, diarrhea and intravenous transfusion. In the study group, duration of diarrhea was shortened by 1.33 days; vomiting disappeared earlier; the number of day for intravenous transfusion was decreased by 1.84. Conclusions Lactose-free diet was useful and effective for infantile rotavirus enteritis. It could relief the symptoms and reduce the course of the disease.