摘要
目的 :探讨慢性心力衰竭 (CHF)患者血清胆固醇酯脂肪酸组成的变化。方法 :采取空腹静脉血测定CHF患者血清TG ,TC ,HDL和LDL水平 ,采用高效液相色谱法测定血清胆固醇酯脂肪酸的组成 ,并与健康对照组进行比较。结果 :两组间血清TC ,TG ,HDL和LDL水平均差异无显著性 ;CHF患者血清胆固醇酯脂肪酸组成中花生四烯酸含量明显降低 (P <0 .0 5 ) ,而亚油酸含量明显增高 (P <0 .0 5 )。结论 :CHF可导致血清胆固醇酯脂肪酸组成发生变化。
Objective To investigate the changes in fatty acid composition of serum cholesteryl esters in patients with chronic heart failure (CHF).Methods The levels of serum TG,TC,HDL,and LDL in 36 patients with CHF and 20 healthy controls were measured and fatty acid cholesteryl esters were determined by high performance liquid chromatography.Results In the patients with CHF,the level of linoleic acid was significantly higher than that in the control group (P<0.05),but the level of arachidonic acid was significantly lower than that in the control group (P<0.05).The levels of TC,TG,HDL,and LDL were not significantly different between the two groups.Conclusion Changes in fatty acid composition of serum cholesteryl esters exist in the patients with CHF.
出处
《湖南医科大学学报》
CSCD
北大核心
2003年第2期165-166,共2页
Bulletin of Hunan Medical University
