血液病受血者抗-HCV检测

Detection of anti-HCV in blood recipients with hematonosis

目的 :观测血液病受血者丙型肝炎病毒 (HCV)感染情况 ,探讨输血前抗 HCV的检测意义。方法 :采用酶联免疫吸附法 (ELISA)检测血液病受血者抗 HCV。观测输血前血液病受血者 176例 ,输血后追踪观察 6～ 12月完成复查 95例 ;并设对照组 417例。结果 :血液病受血者输血前抗 HCV阳性率 ( 5 .6 8%,10 / 176 )明显高于对照组( 0 .72 %,3/ 417;P <0 .0 1)和普外科患者 ( 2 .2 3%,2 1/ 942 ;P <0 .0 5 )。输血后无新感染病例发生。结论 :血液病患者输血前HCV感染值得关注 ,开展输血前抗 HCV检测是必要的。

Objective To observe hepatitis C virus (HCV)infection in blood recipients with hematonosis,and to investigate the significance of anti-HCV detection in the patients.Methods Anti-HCV was detected by enzyme-linked immunosorbent assay (ELISA) in 176 hematonosis patients before blood transfusion,the result of anti-HCV was compared with control (417cases),and 95 blood recipients were followed up for 6～12 months after the transfusion.Results The positive rate of anti-HCV was 5.68%(10/176) in hematonosis patients before transfusion,higher than both in the control [0.72%(3/417),P<0.01] and in the patients with general surgery [2.23%(21/942),P<0.05],and no new infection case was found after the transfusion.Conclusion HCV infectionin in blood recipients with hematonosis should be paid attention to,and the detection of anti-HCV is necessary for patients befoe blood transfusion.