卧床模拟失重生理效应辨证论治效果的初步观察

Priliminary Study on Effects of "Planning Treatment According to Diagnosis" on Physiological Changes during Simulated Weightlessness

目的观察中药对短期卧床模拟失重引起被试者中医证型的论治效果。方法被试者随机分成中药组 (ME)和对照组 (CON)各 5人 ,两组均 - 6°头低位卧床 1 4d ,依据辨证的证侯主法立方 ,随证遣药进行论治。结果ME组无论是中医证机或是对应的生理生化指标 (血浆皮质醇、全血粘度、红细胞变形性、尿木糖排泄率等 )比CON组都能维持卧床前水平 (P <0 .0 5 )或轻度变化。结论卧床 1 4d模拟失重引起的肾阴虚、血瘀、脾气虚之证本药方都有一定调理效果 ,其中对肾阴虚。

Objective To observe effects of the planning treatment according to diagnosis on body syndromes caused by simulated weightlessness. Method Ten subjects underwent HDT-6°for 14 d were randomly divided into the traditional Chinese Medicine group(ME)and control group(CON). Differentiation of syndromes were made and parameters related to the differentiation syndromes, including plasma cortisone, blood viscosity, red cell deformation, excretion rate of urine xylose, and amount of urine were surveyed simultaneously. Result Both differentiation of syndromes and the physiological parameters in group ME could be maintained at the pre bed rest levels or changed only slightly.Conclusion The Chinese herb compound had an adjusting effect on deficiency of kidney Yin, blood stasis, insufficiency of spleen Qi and changes of related physiological parameters caused by 14 d bed rest simulated weightlessness, among which the effect on deficiency of kidney yin and blood stasis were more distinct.