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HER-2基因与乳腺癌化疗效果及预后的关系 被引量：5

Relationship between HER-2 gene and the prognostic effect of chemotherapy in reast cancer
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摘要 HER 2基因编码一分子量为 185kD具有酪氨酸激酶活性的跨膜糖蛋白。约 3 0 %的乳腺癌患者HER 2过表达。HER 2的表达状态与烷化剂、蒽环类、紫杉类等化疗药物敏感性相关 ,与乳腺癌的总生存期、无病生存期相关。进一步的标准化测定及分析方法将对HER
作者 刘芳 江泽飞 宋三泰
机构地区 军事医学科学院
出处 《国外医学（肿瘤学分册）》 2003年第2期110-113,共4页 Foreign Medical Sciences (Cancer Section)
关键词 乳腺癌 化学疗法 疗效 HER-2基因 预后 紫杉类药物
分类号 R737.9 [医药卫生—肿瘤] R730.53 [医药卫生—肿瘤]
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参考文献16

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同被引文献38

  • 1郝希山,冯玉梅,张亮,李晓青,牛昀,肖春花,孙保存.采用单引物扩增法标记的基因芯片技术筛选乳腺原发癌与淋巴结转移癌的差异表达基因[J].中华医学杂志,2005,85(6):385-390. 被引量：24
  • 2钱超文,徐栋,边晔萍,朱慧能,陈丽羽.乳腺癌彩色多普勒超声显像与ER、PR、CerbB-2的表达及意义[J].中国肿瘤,2005,14(5):339-341. 被引量：23
  • 3姜超,张峰,王少军,邹奇飞.COX-2与HIF-1α在肝癌中的表达与相关性[J].中国普外基础与临床杂志,2006,13(2):142-144. 被引量：6
  • 4郭志强,朱辉,马智勇.HER2/neu癌基因及其产物测定在乳腺癌的临床应用[J].中原医刊,2006,33(11):57-59. 被引量：2
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  • 8Wang S, Saboorian MH, Frenkel E, et al. Laboratory assessment of the status of Her -2/neu protein and oncogene in breast cancer specimens: comparison of immunohistochemistry assay with fluorescence in situ hybridisation assays[J]. J Clin Pathol,2000,53:374-381.
  • 9Scheurle D,Jahanzeb M,Aronsohn RS,et al. HER-2/neu expression in archival non-small cell lung carcinomas using FDA-approved Hercep test [J]. Anticancer Res, 2000,20:2091-2096.
  • 10Seliger B, Rongeun Y, Atkins D, et al, HER-2/neu is expressed in human renal cell carcinoma at heterogeneous levels independently of tumor grading and staging and can be recognized by HLA-A2. 1-restricted cytotoxic T lymphocytes[J]. Int J Cancer,2000,87: 349-359.

引证文献5

二级引证文献14

国外医学（肿瘤学分册）
2003年 第2期

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