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新的雌激素受体ERβ在乳腺癌中的研究进展 被引量：5

Progress of studying on a novel estrogen receptor-Erβ in breast cancer
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摘要 新的雌激素受体ERβ解答了单一雌激素受体ERα参与乳腺癌的发生、发展及预后不能解释的部分问题。近年来 ,有关ERβ在乳腺癌中的作用的研究在国外形成了一个新的热点。ERβ可能参与了乳腺癌的发生。
作者 朱建华 江泽飞 宋三泰
机构地区 军事医学科学院
出处 《国外医学（肿瘤学分册）》 2003年第2期98-101,共4页 Foreign Medical Sciences (Cancer Section)
关键词 乳腺癌 雌激素受体 ERΒ 三苯氧胺 耐药机制 预后
分类号 R737.9 [医药卫生—肿瘤]
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参考文献25

  • 1Kuiper GG,Enmark E ,Pelto Huikko M ,et al. Cloning of a novel receptor expressed in rat prostate and ovary[J]. Proc Natl Acad Sci USA, 1996,93(12) : 5925-5930.
  • 2Knowlden JM, Gee JM, Robertson JF, et al. A possible divergent role for the oestrogen receptor alpha and beta subtypes in clinical breast cancer[J]. Int J Cancer, 2000, 89(2) :209-212.
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  • 8Taylor AH, Al Azzawi F. Immunolocalisation of oestrogen receptor beta in human tissues[J]. J Mol Endocrinol, 2000, 24(1):145-155.
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  • 10Girdler F, Browell DA, Cunliffe WJ, et al. Use of the monoclonal antibody DAKO-ERbeta(8D5-1 ) to measure oestrogen receptor Beta in breast cancer cell[J]. Cytometry,2001,45(1) : 65-72.

同被引文献28

  • 1秦凤展,佘明金,汪子书,吴穷,郑荣生.雌激素受体β蛋白在乳腺癌中表达的意义[J].临床肿瘤学杂志,2006,11(8):571-574. 被引量：5
  • 2李杰萍,张浩,叶棋浓.雌激素受体β与乳腺癌[J].生物技术通讯,2006,17(4):637-639. 被引量：2
  • 3Kuiper G G,Enmark E,Pelto Huikko M,et al.Cloning of a novel receptor expressed in rat prostate and ovary[J].Proc Natl Aced Sci USA,1996,93(12):5925-5930.
  • 4Yukiyo T,Raku S,Yuichi S,et al.Turning off estrogen receptor β-mediated transcription requires estregen-dependent receptor proteolysis[J].Mol Cell Biol,2006,:7966-7976.
  • 5Li H Y,Liu H,Wang C H,et al.Deactivation of the kinase IKK by CUEDC2 through recruitment of the phosphatase PP1[J].Nat Immunol,2008,9(5):533-541.
  • 6Zhang P J,Zhao J,Li H Y,et al.CUE domain containing 2 regulates degradation of progesterone receptor by ubiquitin-proteasome[J].EMBO J,2007,26:1831-1842.
  • 7Duong V,Licznar A,Margueron R et al.ERα and ERβ expression and transcriptional activity are differentially regulated by HDAC inhibitors[J].Oncogene,2006,25:1799-1806.
  • 8Zhang X,Leung Y K,Ho S M.AP-2 regulates the transcription of estrogen receptor(ER) β by acting through a methylation hotspot of the ON promoter in prostate cancer cells[J].Oncogene,2007,26:7346-7354.
  • 9Myers E,Fleming F J,Cretty T B,et al.Inverse relationship between ERβ and SRC-1 predicts outcome in endocrine-resistant breast cancer[J].British J Cancer,2004,91:1687-1693.
  • 10Press MF ,Nousek-Gobel N,King WJ,Hetbst GL Immunohistochemiacal assessment of estrogen recept or disfibution in the human endometrium throughout the menstrual cycle[J]. Lab Invest, 1984,51:495-503.

引证文献5

二级引证文献18

国外医学（肿瘤学分册）
2003年 第2期

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