摘要
应用放射性自显影技术,以3H-TdR 为标记物,观察了下颌功能性前仲后大鼠髁突软骨细胞DNA 合成的适应性变化。结果发现下颌前伸后,改变了 TMJ 的生物力学和生物物理环境,刺激了 G0期细胞进入细胞增殖周期,因而髁突软骨生发层内3H-TdR 标记细胞增多。成熟层3H-TdR 标记细胞增多,是由于生发层细胞有丝分裂增加,大量标记的 G1期细胞进入了分化阶段,继发性地使成熟层内标记细胞增多。
The purpose of this study is to investigate the condylar cellular multiplication usingautoradiography after anterior mandibular displacement.Four hours before sacrifice therats received intraperitoneal injections of 1μCi/gram body weight of tritiated thymidineso that the cells synthesizing DNA could be counted.The results showed that the numberof labeled cells in experimental group was significantly increased.It demonstrated thatfunctional anterior protrusion of the mandible can stimulate condylar cartilage multiplica-tion.
出处
《华西口腔医学杂志》
CAS
CSCD
北大核心
1992年第3期214-216,共3页
West China Journal of Stomatology
基金
国家自然科学基金3880832
国家博士点基金880113
