正交设计法催化合成香兰素

ORTHOGONAL DESIGN TO CATALYZE THE SYNTHESIS OF VANILLIN

以 4-甲基 - 2 -甲氧基苯酚为原料 ,经催化氧化可一步合成香兰素。我们采用正交设计法考察了温度、时间、压力、催化剂、氢氧化钠用量等对反应的影响 ,转化率达 94.90 % ,选择性达 85 .0 1 %。

Through catalysis, vanillin can be synthesized from 4-methyl-2-methoxyl phenol. We adopt the orthogonal design and study effect of temperature, time, pressure, catalysis, and the use of sodium hydroxide. The inversion rate reaches 94.90%, and the option reaches 85.01%.