米非司酮配伍米索前列醇用于宫角部残留行钳刮术的效果观察

Mifepristone Combined with Misoprostol in Treatment of the Residue in Comua Uteri.

目的:探索米非司酮配伍米索前列醇在宫角部残留行钳刮术中应用的可行性。方法:随机将30例宫角部残留者分成观察组(16例)和对照组(14例),观察组术前常规口服米非司酮150mg,米索前列醇0.6mg,对照组术前未用药,对两组术中情况进行比较。结果:两组再次刮宫成功率、手术时间、出血量、人工流产综合反应均存在显著性差异(P<0.05)。结论:米非司酮配伍米索前列醇在宫角部残留钳刮术中的应用,减轻了受术者的痛苦,提高了刮宫成功率,具有较大应用价值。

Objective: To evaluate the practicability of using mifepristone and misoprostol before second dilatation and curettage (D&C) to treat the residue in cornua uteri. Methods :30 women with residua in cornua uteri were randomly divided into two groups. 16 women (test group) received mifepristone 150mg and misoprostol 0. 6mg p. o. and the other 14 women (control group) received no drug before second D&C. Results:There was significant difference in the success rate, duration of the ce-cond D&C,amount of bleeding and reaction of artificia abortion syndrome between the two groups. Conclusion: Mifepristone combined with misoprostol is safe, effective and convenient to treat the residue in cornua uteri.