摘要
Cu2-x S nanocrystals(NCs), characterized by low cost, low toxicity, high stability and high photothermal conversion efficiency, provide promising platforms as photothermal agents. Herein, a novel twostep synthesis has been developed for Cu7S4 nanocrystals with hollow structure using the as-prepared copper nanoparticles as starting a solid precursor followed by hot-injection of sulfide source.The Cu7S4 NCs exhibit intense absorption band at Near-infrared(NIR) wavelengths due to localized surface plasmon resonance(LSPR)mode, which can effectively convert 980 nm-laser energy into heat.Moreover, the localized high temperature created by Cu7S4 NCs under NIR irradiation could result in efficient photothermal ablation(PTA) of cancer cells in vivo, demonstrating a novel and promising photothermal nanomaterials.
Cu2-xS. S rianocrystals (NCs), characterized by low cost, low toxicity, high stability and high photothermal conversion efficiency, provide promising platforms as photothermal agents. Herein, a novel two-step synthesis has been developed for Cu7S4 nanocrystals with hollow structure using the as-prepared copper nanoparticles as starting a solid precursor followed by hot-injection of sulfide source.The Cu7S4 NCs exhibit intense absorption band at Near-infrared (NIR) wavelengths due to localized surface plasmon resonance (LSPR) mode, which can effectively convert 980 nm-laser energy into heat. Moreover, the localized high temperature created by Cu7S4 Nes under NIR irradiation could result in efficient photothermal ablation (PTA) of cancer cells in vivo, demonstrating a novel and promising photothermal nanomaterials.
基金
financially supported by the National Natural Science Foundation of China (Grant Nos.21171035 and 51302035)
the Key Grant Project of Chinese Ministry of Education (Grant No.313015)
the PhD Programs Foundation of the Ministry of Education of China (Grant Nos.20110075110008 and 20130075120001)
the National 863 Program of China (Grant No.2013AA031903)
the Science and Technology Commission of Shanghai Municipality (Grant No.13ZR1451200)
the Fundamental Research Funds for the Central Universities
the Hong Kong Scholars Program
the Program for Changjiang Scholars and Innovative Research Team in University (Grant No. IRT1221)
the Shanghai Leading Academic Discipline Project (Grant No. B603)
the Program of Introducing Talents of Discipline to Universities (No. 111-2-04)
