2Motohashi , Kurihara T, Kawase M, et al. Drug resistance reversal, antimutagenicity and antiretroviral effect of phthalimidoand chloroethylphenothiazines[ J ]. Anticancer, 1997, Res, 17:3537-3544.
3Endicott JA, Ling V. The biochemistry of P-glycoproteinmediated multidrug resistance [ J ]. Annu Rev Biochem, 1989,58:137-171.
4Germann UA, Chambers TC, Ambudkar SV, et 8]. Effects of phosphorylation of P-glyceprotein on mtdtidrug resistance [ J ] .J Bioenerg Biomembr, 1995,27(1) :53-61.
5Bell DR, C, erlach JH, Karmer N, et al. Detection of P-glycoprotein in ovarian cancer:a molecular marker associated with mu]tidrug resistance[J] .J Chil Oncoi,1985,3:311-315.
6O' Hare K, Murphy C, Levis R, et al. DNA sequence of the white locus of Drosophila melanogaster[ J]. J Mol Biol, 1984,180:437-455.
7Kamimoto Y, Gatmaitan Z, Hsu J, et al. The function of GPI70, the multidrug resistance gene product, in rat liver canalicular membrane vesicles[J] .J Biol Chem, 1989,264(20) : 11693-11698.
8Roeps PD, Wei LY, Gruz J. Lower electrical membrane potential and altered pH homeostasis in m,,Itidrxqg resistant (MDR) cells: further characterization of a series of MDR cell lines expressing different levels of p-glycoproteinC J]. Biochemistry, 1993,32:11042-11056.
9Kessel D. Exploring mu]tidug resistance using rhodamine 123 [ J]. Cancer Commun, 1989,1 (3) : 145-149.
10Ng WF,Sarangi F, Zastawny RL, et al. Identification of members of the P-glycoprotein multigene family [ J ] . Mol Cell Biol. 1989, 9 : 1224-1232.
5Mc Guire WP,Hoskins WJ,Brady MF,et al.cyclophosphamide and cisplatin compared with paditel and cisplatin in patients with stage Ⅲ and stage Ⅳ ovarian cancer[J].NEngl j MED,1996;334:1
6Nathan FE,Berd D,Sato T,et al.Paclitaxel and tamoxifen,an active regimen for patients with metastatic melanoma[J].Cancer,200; 88(1):79～87
