陕西省健康人群脊髓灰质炎免疫屏障的评价

Evaluation of Immune Level of Poliomyelitis in Healthy Population in Shanxi Province

为了对陕西省近 10年脊髓灰质炎 (脊灰 )的免疫状况做出科学的评价 ,在地理特点不同、经济发展程度各异的 3个地区采集 0～ 39岁健康人群血标本 86 6份测定脊灰抗体。脊灰Ⅰ、Ⅱ、Ⅲ型中和抗体阳性率分别为96 88%、98 0 4%、92 73%,几何平均滴度 (GMT)分别为 1∶2 5 9 30、1∶10 3 6 9、1∶5 2 6 9。表明通过口服脊灰疫苗的常规免疫和强化免疫 ,陕西省健康人群对脊灰已形成牢固的免疫屏障。

In order to evaluate the polio immune level of healthy population in Shanxi Province,we collected 866 serum specimens from 0-39 year old healthy population in three geographical and economical different areas and detected the polio neutralizing antibody.The neutralizing antibody positive rates were 96.88% for polio Ⅰ,98.04% for polio Ⅱ,92.73% for polio Ⅲ and the GMTs were 1∶259.30,1∶103.69 and 1∶52.69 for polio Ⅰ,Ⅱ,Ⅲ respectively.These results indicated that a firm protective barrier against poliomyelitis in healthy population in Shanxi Province has been established through routine immunization and National Immunization Days(NIDs)of OPV.