天津市1999～2001年急性弛缓性麻痹病例及其密切接触者中非脊髓灰质炎肠道病毒监测分析

Analysis of the Non-Polio Enteroviruses lsolated from AFP Cases and the Close Contacts in Tianjin from 1999 to 2001

天津市 1999～ 2 0 0 1年在急性弛缓性麻痹 (AFP)病例及其密切接触者中共分离到非脊髓灰质炎肠道病毒(NPEV) 4 5株 ,其中柯萨奇B组病毒 (Coxsackie ,Cox .B) 15株 ,占 33 3 %;埃可病毒 (ECHO) 13株 ,占 2 8 9%;不能定型的病毒 17株 ,占 37 8%。从时间分布看 ,Cox .B病毒主要集中在 6～ 8月 ,占 86 7%;ECHO病毒主要集中在 8～ 9月 ,占 92 3%,显示NPEV主要集中在夏秋季。从地区分布看 ,45株NPEV中有 4株分离自市区 ,占 8 9%;41株分离自郊县 (区 ) ,占 91 1%,提示感染肠道病毒与卫生条件有关。

This paper reported the type analysis of the non-polio enteroviruses (NPEV) isolated from AFP cases and the close contacts in Tianjin from 1999 to 2001.There were 15 strains of Coxsackie B virus(33.3%),13 strains of ECHO virus (28.9%) and 17 strains of unclassified virus (37.8%) isolated from a total of 45 NPEV strains.According to time distribution,most Coxsackie B viruses were isolated from June to August(86.7%) and most ECHO viruses were from August to September(92.3%).In June and September was the peak of NPEV infection.According to regional distribution,there were 4 NPEV strains isolated from urban district(8.9%),41 strains from suburban district and county(91.1%),this suggests the infection of NPEV is related to hygienic conditions.