探讨术中冰冻诊断乳腺癌的临床价值及影响准确率的临床因素

To investigate the clinical value of intraoperative frozen diagnosis of breast cancer and the clinical factors affecting the accuracy of the diagnosis of breast cancer

目的:探讨术中冰冻诊断乳腺癌的临床价值及影响准确率的临床因素;方法:选择我院2013年3月至2016年2月收治的100例乳腺癌患者,回顾性分析患者的临床诊断资料和术中冰冻切片资料,选择世界卫生组织2003年版乳腺癌分类及患者术后病理学检验结果来对术中冰冻诊断的准确率进行判断,并对影响术中诊断准确率的临床因素进行探讨;结果:Ⅰ级、Ⅱ级、Ⅲ级的分级符合率分别为69.6%、75.5%、86.4%,术中冰冻诊断和术后病理诊断的整体符合率为76.0%(76/100);术中冰冻诊断的分级符合率随着组织级别的增加而增加;在癌肿组织学大小≤3cm的78例患者中,组织学大小一致的共有65例;在癌肿组织学大小>3cm的22例患者中,组织学大小一致的共有21例;两者诊断的整体符合率为86.0%(86/100);分析发现影响术中冰冻诊断准确率的临床因素主要为X线钼靶存在钙化点减少、乳腺肿瘤发生在绝经后。结论:临床中在对乳腺癌患者进行诊断时,术中冰冻诊断具有非常重要的作用,临床诊断准确率较高,对于临床治疗方案的制定非常重要。

Objective:To exp10 re the clinical factors and clinical value of intraoperative frozen affect the diagnostic accuracy of breast cancer;Methods:100 cases of breast cancer patients in our hospital from March 2013 to February 2016,were retrospectively analyzed the clinical diagnosis and intraoperative frozen section data,2003 edition of breast cancer patients and the classification of WHO after patholOgical examination results to determine the accuracy of intraoperative frozen section diagnosis,discusses the clinical factors and the diagnostic effect of intraoperative accuracy;results:Ⅰ grade,Ⅱ grade,Ⅲ grade coincidence rate is respectively 69.6%,75.5%,86.4%,intraoperative frozen section diagnosis and postoperative patholOgical diagnosis of the whole the coincidence rate was76%(76/100);classification of intraoperative frozen section diagnosis coincidence rate increased with the increase of the organization level;in 78 cases the size of less than 3cm cancer tissues in patients with histological size by total 65 cases;in cancer tissues learn the size of > 3 cm of the 22 patients,histological size consistent with a total of 21 cases;between the diagnostic coincidence rate was 86.0%86/100;analysis the effect of operation in frozen clinical factors of diagnostic accuracy rate of mammographic calcifications decrease as the main,mammary gland tumorigenesis in postmenopausal.Conclusion:clinical in diagnosis of breast cancer patients,intraoperative frozen plays a very important role in the diagnosis,clinical diagnosis accurate rate is higher,for the formulation of clinical treatment is very important.