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他汀类药物(立普妥)对冠心病患者血脂水平的影响观察 被引量:4

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摘要 目的:探讨立普妥在不同剂量下的降脂效果及降脂安全性。方法:以本院2014年7月~2015年7月接诊收治的158例冠心病伴高脂血症的老年患者为研究对象,将患者按照入院先后顺序随机分为对照组,立普妥1组及立普妥2组,其中对照组在冠心病基础治疗上加服蒲参胶囊,立普妥1组加服立普妥20mg/日,立普妥2组加服立普妥40mg/日,治疗疗程为15周,对患者服药前、服药5周、服药15周时的血脂水平指标进行记录对比,对比降脂效果。结果:患者经过立普妥治疗后,TC、TG、LDL-C降低明显,效果显著(P<0.05);三组对比,立普妥2组在降低心血管不良事件发生率上有明显优势(P<0.05)。结论:对于老年冠心病患者来说,按40mg/日的剂量进行立普妥药物服用能更好降低TC、TG、LDL-C,升高HDL-C,降脂效果好,治疗中无不良反应,能明显减少心血管事件发生。
作者 李进
出处 《中国农村卫生》 2019年第4期46-47,共2页
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