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同源异形盒基因与肿瘤

Homeobox genes and cancer
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摘要 同源异形盒基因是一类特殊的转录调节因子 ,其表达蛋白通过序列特异性DNA结合活性 ,调控胚胎的发育和分化。近年来研究发现 ,同源异形盒基因异常表达与肿瘤的发生和发展密切相关。现综述有关同源异形盒基因在肿瘤发生。
作者 宋自芳
出处 《国外医学(肿瘤学分册)》 CAS 2003年第3期163-166,共4页 Foreign Medical Sciences (Cancer Section)
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参考文献28

  • 1Cillo C, Cantile M, Faiella A, et al. Homeobox genes in normal and malignant cells[J]. J Cell Physiol, 2001, 188(2): 161-169.
  • 2Soubeyran P, Haglund K, Garcia S, et al. Homeobox gene Cdxl regulates Ras, Rho and PI3 kinase pathways leading to transformation and tumorigenesis of intestinal epithelial cells [J ]. Oncogene,2001, 20(31) : 4180-4187.
  • 3Cillo C, Faiella A, Cantile M, et al.Homeobox genes and cancer[J]. Exp Cell Res, 1999, 248(1): 1-9.
  • 4Gorski DH, Walsh K. The role of homeobox genes in vascular remodeling and angiogenesis[J]. Circ Res, 2000, 87(10): 865-872.
  • 5Kim S, Domon Dell C, Wang Q, et al . PTEN and TNF-alpha regulation of the intestinal-specific Cdx-2 homeobox gene through a PI3K, PKB/Akt, and NF-kappaB-dependent pathway[J]. Gastroenterology, 2002, 123(4): 1163-1178.
  • 6Irving C, Mason I. Signalling by FGF8 from the isthmus patterns anterior hindbrain and establishes the anterior limit of Hox gene expression[J]. Development, 2000, 127(1) : 177-186.
  • 7Briscoe J, Sussel L, Setup P, et al. Homeobox gene Nlcx2.2 and specification of neuronal identity by graded Sonic Hedgehog signalling[J]. Nature, 1999, 398(6728): 622-627.
  • 8Ronshaugen M, McGinnis N, McGinnis W. Hox protein mutation and macroevolution of the insect body plan[J ]. Nature, 2002, 415(6874) : 914-917.
  • 9Abate Shen C. Deregulated homeobox gene expression in cancer:cause or consequence[J]? Nat Rev Cancer, 2002, 2(10) : 777-785.
  • 10Rao MK, Maiti S, Ananthaswamy HN, et al. A highly active homeobox gene promoter regulated by Ets and Spl family members in normal granulosa cells and diverse tumor cell types [ J ]. J Biol Chem, 2002, 277(29): 26036-26045.

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