康瑞保凝胶治疗瘢痕患者57例

Treatment of 57 Cases of Hypertrophic Scars and Keloids with Contractubex Gel

目的 :观察康瑞保凝胶对小面积增生性瘢痕及瘢痕疙瘩的临床疗效。方法 :增生性瘢痕及瘢痕疙瘩患者5 7例 ,外搽康瑞保凝胶 ,qid ,涂药后 ,局部按摩 5～ 10min以促进药物的吸收 ,疗程 6个月 ,疗程结束后 ,对瘢痕的面积、硬度、颜色等改变及患者瘙痒、疼痛等自觉症状改善情况进行记分。结果 :康瑞保凝胶对瘢痕总有效率 6 1.4% ;对病程在 1a内的患者总有效率 76 .7% ,对病程在 1a以上的患者有效率 44.4%。结论 :康瑞保凝胶为临床治疗增生性瘢痕及瘢痕疙瘩 ,特别是病程较短的增生性瘢痕及瘢痕疙瘩提供了一个新的有效方法。

Objective:To test the clinical effectiveness of contractubex gel in the treatment of small area hypertrophic scars and keloids. Methods:Hypertrophic scars and keloids in 57 patients were painted with contractubex gel four times a day in a period of 6 consecutive months. After each painting, the local areas were rubbed gently for 5-10 min to promote absorption of the drug. Changes in the size, hardness, and color of the scars as well as the patients' symptoms including itch and pain were scored at the termination of the course of treatment. Results:The overall effective rate of contractubex gel was 61.4% in all of the patients studied. In patients with a duration of illness within a year, the effective rate was 76.7%, while that in those with a course longer than a year was 44.4%. Conclusion:Contractubex gel was shown to be a new and effective drug for the treatment of hypertrophic scars and keloids, in particular for those patients with a relatively short course of disease.