复方消痹药浴包洗浴治疗类风湿性关节炎活动期108例临床观察

Clinical observation on 108 cases of rheumatoid arthiritis at active stage treated by bathing with Compound Xiaobi Yaoyu Bao

目的;观察复方消痹药浴包洗浴治疗类风湿性关节炎活动期的临床疗效。方法:将169例类风湿性关节炎活动期患者随机分为治疗组108例,每日用复方消痹药裕包洗浴1次,每次50分钟,对照组61例,每日用1％扶他林乳胶剂外涂2次,用药30天后观察患者临床疗效、症状体征、红外线热象图、炎性标志物、血液流变学的变化。结果;治疗组临床愈显率77.8％,总有效率92.6％,主要症状及体征均有显著改善(P<0.05或P<0.01);红外线热象图检测显示患者双手指关节表面温度显著下降(P<0.05或P<O.01);炎性标志物检测显示血沉(ESR)、C-反应蛋白(CRP)均有显著性下降(P<0.01);血液流变学检测显示,各项指标均有显著性降低(P<0.05或P<0.01)。复方消痹药浴包治疗组各疗效指标均明显优于对照组(P<0.05或P<0.01)。结论:复方消痹药浴包洗浴对类风湿性关节炎活动期具有显著的治疗作用。

Objective: To observe the therapeutic effect of bathing with Compound Xiaobi Yaoyu Bao on rheumatoid arthritis. Methods: 169 cases of rheumatoid arthritis at active atage were randomly divided into treatment group (n = 108) and control group (n = 61). and were treated by bathing with Compound Xiaobi Yaoyu Bao and external smearing of 1% Voltaren emulsion respectively. After treatment of 30 days, therapeutic effects, symptoms and signs, infra-red thermogram, inflammatory markers and hemorheologic indexes were investigated. Results: Clinicaly cured rate and total effective rate were 77. 8% and 92. 6% respectively, main symptoms and signs improved significantly in treatment group. Examination of infra-red thermogram showed that temperature on surface of bilateral finger joints decreased significantly (P<0. 05 or P<0. 01). inflammatory markers ESR and CRP decreased significantly (P<0. 01). and hemorheologic indexes decreased significantly (P<0. 05 or P<0. 01) in the patient. And all the indexes in treatment group were superior to those in control group (P< 0. 05 or P<0. 01). Conclusion: Bathing with Compound Xiaobi Yaoyu Bao has obvious therapeutic action on rheumatoid arthritis at active stage.