多肽:N-乙酰氨基半乳糖转移酶2(Polypeptide:N-Acetylgalactosaminyltransferases,pp-GalNAc-T2,E.C.2.4.1.41)的mRNA表达谱研究
被引量：1
摘要
多肽:N-乙酰氨基半乳糖转移酶2是O-糖链合成第一步的糖基转移酶,而O-糖基化与血管内皮细胞的功能密切相关。随着近年来人类基因组计划的迅速发展,人们对糖基转移酶的功能也开始有了新的认识。本文采用RT—PCR法观察了六种不同组织中PP-CallNAC-T2的表达水平,发现PP—GalNAc—T2在胃肠道粘膜等呈高表达,在脑组织中也有一定的表达,提示它在不同组织中的分布与组织功能存在相关性,值得进一步研究。
出处
《中国血液流变学杂志》
CAS
2003年第1期24-25,79,共3页
Chinese Journal of Hemorheology
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引证文献1
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1吴琛,葛建峰,张博,马思思,刘芳铭,王媛媛,田焕娜,刘晓波,张晓康,李秦剑.乙酰氨基半乳糖转移酶14(GALNT14)在毕赤酵母中的表达纯化及活性鉴定[J].中国生物工程杂志,2011,31(11):58-63.
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1仇灏,刘可人,朱琍燕,吴士良.人多肽:N-乙酰氨基半乳糖转移酶2(ppGalNAc-T2)RNA干扰载体的构建及鉴定[J].江苏大学学报（医学版）,2007,17(2):102-104. 被引量：2
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