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NT-proBNP、超声心动图及血气分析联合应用对急性左心衰诊断和预后的影响 被引量:9

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摘要 目的:探讨联合运用N-末端B型利钠肽原(NT-pro BNP)检测、超声心动图及血气分析对急性左心衰患者的诊断价值和预后的影响。方法:本院2008年1月至2010年6月NT-pro BNP检测开展前收治的急性左心衰患者为A组(对照组1,n=96);2011年7月至2013年12月NT-pro BNP检测开展后收治的急性左心衰患者为B组(实验组,n=98);2011年7月至2013年12月NT-pro BNP检测开展后因急性呼吸困难同时行NT-pro BNP检测、超声心动图及血气分析排除急性左心衰的患者为C组(对照组2,n=54)。记录并分析B、C组的诊断数据;对A、B组患者随访6个月,比较A、B组的平均住院日、再住院率、病死率和人均住院费用。结果:联合应用NT-pro BNP检测、超声心动图及血气分析可取得93.4%对急性左心衰诊断准确性,高于联合应用NT-pro BNP、超声心动图诊断准确性(90.1%)及单独使用NT-pro BNP检测或超声心动图诊断准确性(分别是82.8%、76.3%)。B组平均住院日(8.2±0.9)d短于A组(11.1±0.8)d(P<0.05);B组再住院率9.2%、病死率5.1%低于A组再住院率15.6%、病死率9.4%(P<0.05);B组平均住院费用(9 324±462)元低于A组(12 315±574)元(P<0.05)。结论:联合运用NT-pro BNP检测、超声心动图及血气分析可提高急性左心衰诊断准确性,并可降低急性左心衰患者平均住院日,改善预后并节省住院费用。
出处 《南京医科大学学报(自然科学版)》 CAS CSCD 北大核心 2015年第8期1163-1166,共4页 Journal of Nanjing Medical University(Natural Sciences)
基金 盐城市医学科技科研课题资助(YK2010070)
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