白介素-16与支气管哮喘关系的研究

Relationship between Interleukin 16 and Bronchial Asthma

白介素-16(IL-16)作为一种淋巴细胞趋化因子,参与了哮喘发病的早期调节,通过与细胞表面的CD4分子结合引起CD4+T细胞、嗜酸性粒细胞和单核细胞的趋化性活动并在活化中发挥重要作用,参与哮喘气道炎症形成.

Interleukin 16 takes part in the early regulation of bronchial asthma as a lymphocyte chemostatic factor, playing important role by combination with CD4 molecule on cellular surface to accumulate eosinophiles, monophiles, CD4 +T.