摘要
糖尿病肾病(DN)是糖尿病(DM)的主要微血管并发症之一,其发病机制尚未明确,研究表明铁过载导致氧化应激增强和一些炎性因子增多,而氧化应激和炎性因子在DN的发生、发展中起着重要的作用.因此,铁过载可能会促进DN的发生与发展.
Diabetic nephropathy(DN)is one of the major microvascular complications of diabetes mellitus(DM), and the pathogenesis is not yet clear. Studies have shown that iron overload leads to the increase of oxidative stress and inflammatory cytokines. However, oxidative stress and inflammatory cytokines play an important role in the occurrence and development of DN. So, iron overload maybe promote the occurrence and development of DN.
出处
《内蒙古民族大学学报（自然科学版）》
2016年第1期81-85,93,共6页
Journal of Inner Mongolia Minzu University：Natural Sciences
基金
内蒙古自治区高等学校科学研究项目(NJZY11205)
关键词
铁过载
糖尿病
糖尿病肾病
氧化应激
炎性因子
Iron overload
Diabetes mellitus
Diabetic nephropathy
Oxidative stress
Inflammatory cytokines
