炎性因子与冠脉斑块易损性的研究进展被引量：6

RESEARCH PROGRESS OF THE CORRELATION BETWEEN SERUM INFLAMMATORY FACTORS CORONARY HEART DISEASE PLAQUE VULNERABILITY

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摘要冠状动脉粥样硬化斑块是由于冠脉血管内膜损害后,血管内皮细胞通透性增加,脂质及其他有害物质沉积于血管内膜下形成的。而斑块脂质核心的大小、纤维帽的薄厚、炎症反应剧烈程度决定斑块的稳定性,炎症反应是导致斑块破裂的重要因素,炎性因子是炎症反应的标记物,可反应炎性反应的活跃性,进而可预测斑块的稳定性,现就冠心病冠脉斑块的炎性标志物做一综述。 Atherosclerosis damages the endothelium and make endothelial cells permeable to cholesterol as well as other harmful substances,resulting in atherosclerosis formation. The lipid core 、fibrous and inflammation determine the stability of artery plaques. Inflammation play an important role in leading the rupture. Inflammatory factors can reflect inflammation and the stability of artery plaques,and is an marker of inflammation.

作者肖学慧陈照宇刘艳阳张越

机构地区内蒙古医科大学附属医院心内科

出处《内蒙古医科大学学报》 2015年第S1期173-176,182,共5页 Journal of Inner Mongolia Medical University

关键词炎性因子冠心病冠脉斑块稳定性 Inflammatory factors,Serum inflammatory factors Coronary heart disease Plaque stability

分类号 R541.4 [医药卫生—心血管疾病]

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1S. I. van Leuven,R. Franssen,J. J. Kastelein,M. Levi,E. S. G. Stroes,P. P. T.Systemic inflammation as a risk factor for atherothrombosis. Rheumatology . 2008
2H R S Girn,N M Orsi,S Homer-Vanniasinkam.An overview of cytokine interactions in atherosclerosis and implications for peripheral arterial disease. Vascular Medicine . 2007
3Wong Guang W,Wang Jin,Hug Christopher,Tsao Tsu-Shuen,Lodish Harvey F.A family of Acrp30/adiponectin structural and functional paralogs. Proceedings of the National Academy of Sciences of the United States of America . 2004
4Wong G William,Krawczyk Sarah A,Kitidis-Mitrokostas Claire,Revett Tracy,Gimeno Ruth,Lodish Harvey F.Molecular, biochemical and functional characterizations of C1q/TNF family members: adipose-tissue-selective expression patterns, regulation by PPAR-gamma agonist, cysteine-mediated oligomerizations, combinatorial associations and metabolic functions. The Biochemical Journal . 2008
5Peterson, Jonathan M.,Aja, Susan,Wei, Zhikui,Wong, G. William.CTRP1 protein enhances fatty acid oxidation via AMP-activated protein kinase (AMPK) activation and acetyl-CoA carboxylase (ACC) inhibition. Journal of Biological Chemistry . 2012
6Winzeler B F,Christ-Crain M.[Hormones as biomarkers for diagnosis and prognosis]. Praxis . 2012
7Kopterides P,Tsangaris I.Procalcitonin and sepsis: recent data on diagnostic utility prognostic potential and therapeutic implications in critically ill patients. Minerva Anestesiologica . 2012
8Sentürk Tunay,Cordan Jale,Baran Ibrahim,Ozdemir Bülent,Güllülü Sümeyye,Aydinlar Ali,G?ral Güher.Procalcitonin in patients with acute coronary syndrome: correlation with high-sensitive C-reactive protein, prognosis and severity of coronary artery disease. Acta Cardiologica . 2007
9Christoph R. Sinning,Jan-Malte Sinning,Andreas Schulz.Association of Serum Procalcitonin With Cardiovascular Prognosis in Coronary Artery Disease - Results From the AtheroGene Study. Circulation Journal . 2011
10Atao?lu H E,Yilmaz F,Uzunhasan I,Cetin F,Temiz Lü,D?venta? Y E,Kaya A,Yenigün M.Procalcitonin: a novel cardiac marker with prognostic value in acute coronary syndrome. The Journal of international medical research . 2010