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持续血液滤过治疗全身炎症反应综合征的临床应用

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摘要 全身炎症反应综合征(SIRS)病情凶险,病死率高,易转化成为多器官功能障碍综合征(MODS),是重症监护病房治疗的难点。清除炎症介质及细胞因子和循环中的内毒素,减轻炎性反应,阻断全身炎症反应继续发展及MODS的进一步恶化。"连续血液滤过"(CAVH)是近年来在治疗SIRS/MODS领域中逐渐发展起来的具有理论和实践双重价值的新技术,是一种连续的、缓慢的血液净化模式,在SIRS,MODS中的应用越来越广泛,显示了很好的疗效。1 SIRS的发病机制SIRS是机体在遭受严重创伤、休克、感染及大手术等急性损害24 h后,不能维持内环境稳定的临床综合征,强调病变的动态性和可逆性。现已明确全身炎症反应综合征(SIRS)是MODS的重要诱因。有学者认为是严重感染或创伤等损害作用于机体后引发的应答性反应。大量炎症介质释放入血液循环,刺激炎症介质瀑布样释放,导致SIRS,继而导致炎性反应失控。
作者 裴秀峰
出处 《内蒙古医学杂志》 2009年第S3期42-43,共2页 Inner Mongolia Medical Journal
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